The Northern Hemisphere's showpiece international tournament returns tonight when the old enemy arrive at a red-hot Miillennium Stadium.
Recent history does not read well for the Red Rose nation, who have not won in Cardiff since 2003.
After a fortnight of talking, Wales and England face a game which could define their respective seasons.
In his two biggest selection calls, Warren Gatland has chosen Ospreys Paul James and Craig Mitchell as his props in place of injured first-choice pair Gethin Jenkins and Adam Jones.